Not every probiotic needs to be refrigerated, and just because one does doesn't mean it's better than one that doesn't. Align is made by Proctor & Gamble, a 71 billion dollar company.
Up until early 2016 we were only able to culture around 1% of gut microbes [1, 2]. Looks like you're using new Reddit on an old browser. They are also not interchangeable with probiotics, except for ones sourced from fermented foods, like Garden Of Life products. So these are not necessarily a "cure for constipation". I have been taking Culturelle probiotics ever since I was diagnosed. Florastor is one of the top selling and recommended probiotics, but yet has the fewest check marks. I didn't have any issues with the culturelle except heartburn, which I don't have on the Align. I started a list below (stickied comment) of products and the sources of their strains. I do have a question. *These statements have not been evaluated by the Food & Drug Administration. VSL #3 Powder Packets require a prescription. This 2017 study showed that two different batches of VSL#3 had remarkably different impacts, with one of them worsening intestinal permeability: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532379/. FLORATUMMYS PROBIOTICS SPRINKLES PACKETS FOR KIDS contains only 5 ingredients: 2 Friendly probiotics (5 billion live cells), Prebiotic (FOS), Silica (natural mineral that absorbs toxins in the GI tract) and the powder made of potatoes. Most human-derived probiotics are native strains that would be the most likely to perform native functions, and colonize the gut (but still typically do not colonize). I've been armchair researching the importance of maintaining a healthy/balanced gut microbiome for awhile now (particularly its impact on mental health and chronic inflammation), but it's a fairly new field of study and most articles/sellers still conflate any and all probiotics as beneficial, failing to recognize the difference in biological effects between the various strains and food vs human derived sources. So I tried that with Jarrow's s.boulardii, both overnight at room temp and fridge temp. Since their recommended dose is two capsules daily, I calculated the daily cost at $1.46 or $0.73 per capsule. This is one I haven't tried yet but looks extremely promising (EDIT: nope, another let down. There are 2 in the recommendations section. EDIT: here's a project with a list of strains that /u/markus_naslund has started: https://old.reddit.com/r/HumanMicrobiome/comments/aceyab/commercially_available_probiotic_strain_database/. I tried culturelle, but in my experience it did not help at all and even possibly made my symptoms worse. I have also benefited largely from this phage product. And after an FMT or two, Align makes the soil-bac-symptoms worse, but the Lactobacillus probiotics are still helpful. Join us if you want to keep up to date with how our microbiomes impact all areas of human health, and to see what implications it will have for you.
VSL#3 - personally this has worked wonders for me. To get the most benefit you want the stuff thats not pasteurized, and requires refrigeration(IE its still alive). I would recommend introducing each product one at a time (for a few days each) so you can see what effect it has. I put some links at the bottom where I tried to do similar things and the outcome was that certain foods give rise to specific kinds of microbes that are most able to use those substrates as food sources. But someone reported it has similar effects to fermented foods.
The recommendations for neonates are essentially the same as adults: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163616/ - also confirms the importance of specific strains & human-sourced strains. I've seen some difference but not much. If Culturelle … IE: we used to be naturally exposed to these things therefore they must be good for us. It's the same/similar as any other food-sourced product IMO. What matters is what those studies showed it to be effective/ineffective/harmful for. There are however 90 capsules per bottle. They each contain amounts that worked in the studies done on them.
I think most/all human-derived strains are patented, thus you'll only find them in one product. Soil based probiotics are not the sam live bacteria that normally exist in our gut. I haven't tried most of the probiotics you mentioned. Food Recall Warning (Allergen) - Certain Goodfood brand Roasted Sweet Potato Power Bowls recalled due to undeclared almonds, pecans, wheat and gluten, Celiac.com Community Latest Posts RSS Feed. What works for me might not work for you. Multiple reports of it curing IBS-C. BioGaia Gastrus has one or more human-sourced strains, but also has some unnecessary additives that might cause problems for some people. Celiac Disease Pre-Diagnosis, Testing & Symptoms, Trader Joe's brand Gluten Free Battered Halibut Issues Allergy Alert on Undeclared Wheat and Milk Allergens, Gluten Busters: Gluten-Free Product Alerts by Celiac.com. I have tried Renew Life 50 billion, Align, Florastor, and Lifeway Kefir. With this in mind, I have a history of a lot of different antibiotics (along with CFS, IBS-D and others). Similar to the soil bacteria warning, I have not only found these to typically be harmful to myself, but I've seen a number of reports of people taking these multi-strain, high CFU count products and reporting that it caused them "SIBO", fatigue, and other detrimental side effects. Have you tried Kombucca tea? So I'm lining the Align probiotic and Culturelle up against each other in a duel. When we compare probiotic supplements we need to define our comparison for a specific targeted condition, otherwise the comparison is useless.
AOR Probiotic 3: Has 3 species which are uncommon in other products.
The microbiome is a rapidly growing area of research, and has been linked to nearly every illness currently beyond medical capabilities. Most clinical studies with Lactobacillus GG have used 10 to 20 billion viable cells per day. May 2018: I read that nutritional yeast is made by growing the yeast on molasses.
Once daily unless you can afford more. The above information will change with time, and I'll make regular updates. Try the most backed/studied human-sourced probiotics first. But they will not colonize the gut, or perform the necessary roles of native strains. There's a big difference between strains (and this term is often misused), and where the probiotic was sourced from. Their website shows, that all their liquid, soft gel, and gummie products are encapsulated and bottled in the USA, but I still don’t know where their adult probiotics are made. If you find this overwhelming, just try the probiotics in the "recommendations" section one at a time, while minimizing fermented food intake. If you find that you like it you can brew your own. **Studies, articles, and discussion related to the human microbiome. The vast majority are food-sourced so it might be easier to just keep a list of human-sourced. What's effective for someone is going to vary between person to person because it depends on the current microbes that are in each person's gut. That particular Reuteri product seemed to, at one point, benefit me significantly more than a very similar product from the same company with a different strain of L.reuteri. Align & Culturelle are the two most backed strains in the literature, and both are also sourced from humans. Studies show that combination of probiotics with both lactobacillus and bifidobacterium can be more beneficial for optimal digestive health.
Fermented foods are generally quite oversold and can have detrimental effects. Try to match your symptoms to a probiotics benefits. What method did you use to test the probiotics? It really does come down to your individual microbiological balance. I make my own sauerkraut but t hasn't worked that well :/. Align & Culturelle are the two most backed strains in the literature, and both are also sourced from humans. paisleydaisy, October 17
“You’ll ♥ the Culturelle advantage,” says the maker of Culturelle, a supplement containing probiotic (“good”) bacteria.
Made me poop more and increased fatigue.
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